Minimal role for the alternative pathway in complement activation by HIT immune complexes.
Barnes AP, Khandelwal S, Sartoretto S, Myoung S, Francis SJ, Lee GM, Rauova L, Cines DB, Skare JT, Booth CE Jr, Garcia BL, Arepally GM., J Thromb Haemost., 2022
https://pubmed.ncbi.nlm.nih.gov/35996342/
Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions.
Booth CE Jr, Powell-Pierce AD, Skare JT, Garcia BL., Front Immunol., 2022
https://pubmed.ncbi.nlm.nih.gov/35693799/
A Structural Basis for Inhibition of the Complement Initiator Protease C1r by Lyme Disease Spirochetes.
Garrigues RJ, Powell-Pierce AD, Hammel M, Skare JT, Garcia BL., J Immunol., 2021
https://pubmed.ncbi.nlm.nih.gov/34759015/
Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by Lyme disease spirochetes.
Xie J, Zhi H, Garrigues RJ, Keightley A, Garcia BL, Skare JT., PLoS Pathog., 2019
https://pubmed.ncbi.nlm.nih.gov/30897158/
Biomechanics of Borrelia burgdorferi Vascular Interactions.
Ebady R, Niddam AF, Boczula AE, Kim YR, Gupta N, Tang TT, Odisho T, Zhi H, Simmons CA, Skare JT, Moriarty TJ., Cell Rep., 2016
https://pubmed.ncbi.nlm.nih.gov/27568563/
Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex.
Garcia BL, Zhi H, Wager B, Höök M, Skare JT., PLoS Pathog., 2016
https://pubmed.ncbi.nlm.nih.gov/26808924/
BB0744 Affects Tissue Tropism and Spatial Distribution of Borrelia burgdorferi.
Wager B, Shaw DK, Groshong AM, Blevins JS, Skare JT., Infect Immun., 2015
https://pubmed.ncbi.nlm.nih.gov/26150534/
The BBA33 lipoprotein binds collagen and impacts Borrelia burgdorferi pathogenesis.
Zhi H, Weening EH, Barbu EM, Hyde JA, Höök M, Skare JT., Mol Microbiol., 2015
